Anti N-Methyl-D-Aspartate Receptor Encephalitis with Ovarian Teratoma: A Dilemma in Diagnosis

Lee CL, Zainuddin AA, Abdul Karim AK, Yulianty A, lAW ZK, Md Isa N, Nor Azlin MI

Abstract


We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery.

Keywords


Anti-N-Methyl-D-Aspartate receptor, encephalitis, ovarian tumour, psychosis, teratoma

Full Text:

PDF


DOI: http://dx.doi.org/10.17576/JSA.2016.0601.15

Refbacks

  • There are currently no refbacks.


e-issn 2231-7481