In vitro Antiplasmodial Activity and Cytotoxicity of Ten Plants Used as Traditional Medicine in Malaysia
Keywords:
Plasmodium falciparum, Plant, Antiplasmodial activity, Cytotoxicity, MalaysiaAbstract
Dichloromethane and methanolic extracts of each plant were tested for their antiplasmodial activity on chloroquineresistant strain of Plasmodium falciparum (FCB strain), based on lactate dehydrogenase activity. Cytotoxicity was assessed with the MTT test on MRC-5 human diploid embryonic lung cells. Most extracts of ten selected plants used in Malay traditional medicine in Malaysia had activity in vitro. This supports continued investigations of traditional medicine in the search for new antimalarial agent. The compounds responsible for the observed antiplasmodial effects are under investigation.Downloads
Published
Issue
Section
License
It is a condition of publication in the Journal that authors assign copyright to the Penerbit, Universiti Kebangsaan Malaysia, using the form available on the Copyright Assignment Form page. This ensures that requests from third parties to reproduce articles are handled efficiently and consistently and will also allow the article to be as widely disseminated as possible. In assigning copyright, authors may use their own material in other publications provided that the Journal is acknowledged as the original place of publication, and Penerbit Universiti Kebangsaan Malaysia is notified in writing and in advance.
Our journal offers an open access articles, which is under the Creative Common license type : Attribution-NonCommercial-ShareAlike (CC BY-NC-SA)
