The Epidermal Mucus Extract of Clarias Batrachus Inhibits Gram Negative Bacteria Growth

Authors

  • AHMAD ZORIN SAHALAN Universiti Kebangsaan Malaysia
  • ENGKU SHARMILA Universiti Kebangsaan Malaysia
  • NAZAHIYAH SULAIMAN Universiti Kebangsaan Malaysia

Keywords:

Clarias batrachus, cat fish, epidermal mucus, antibacterial

Abstract

Recently, epidermal mucus of fish has been identified as a rich biological source of various bioactive substances, particularly antibacterial peptides. This study was conducted to identify the potential of epidermal mucosa of Clarias batrachus as a source of antibacterial material. Mucosal samples were collected from C. batrachus epidermis and extracted using an aqueous extraction method. Antibacterial activity of the crude epidermal mucus extract was determined by using spectrophotometric method. As a result there was antibacterial activity by the mucus extract against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). The results of this study supports the role of mucus as a part of body immune system with antibacterial peptide as a component of innate body immune system. Hence, these findings can be used as one of the first steps towards the development of new class antibiotics. DOI : http://dx.doi.org./10.17576/JSKM-2018-12

Author Biographies

AHMAD ZORIN SAHALAN, Universiti Kebangsaan Malaysia

Program Sains BioperubatanPPSDKG, Fakulti Sains Kesihatan, UKMJalan Raja Muda Abd. Aziz50300, Kuala Lumpur 

ENGKU SHARMILA, Universiti Kebangsaan Malaysia

Program Sains BioperubatanPPSDKG, Fakulti Sains Kesihatan, UKMJalan Raja Muda Abd. Aziz50300, Kuala Lumpur

NAZAHIYAH SULAIMAN, Universiti Kebangsaan Malaysia

Jabatan Perkhidmatan VeterinarKementerian Pertanian dan Industri Asas Tani62624 Presint 4, Wilayah Persekutuan Putrajaya

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Published

2018-06-05

Issue

Vol. 16 (2018): Special Issue (Faculty of Health Science Silver Jubilee 2017)

Section

FSK Silver Jubilee (Article)

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