Doses to Organs at Risk Calculated Using Plato and Oncentra Softwares in Intracavitary Brachytherapy

Authors

  • Chen Suk Chiang Medical Radiation Programme, School of Health Sciences, Health Campus Universiti Sains Malaysia 16150 Kubang Kerian, Kelantan, Malaysia
  • Nor Hafizah Abdullah Medical Radiation Programme, School of Health Sciences, Health Campus Universiti Sains Malaysia 16150 Kubang Kerian, Kelantan, Malaysia
  • Reduan Abdullah Medical Radiation Programme, School of Health Sciences, Health Campus Universiti Sains Malaysia 16150 Kubang Kerian, Kelantan, Malaysia & Hospital Universiti Sains Malaysia, Health Campus, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia
  • Mazurawati Mohamad Hospital Universiti Sains Malaysia, Health Campus, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia
  • Ahmad Zakaria Medical Radiation Programme, School of Health Sciences, Health Campus Universiti Sains Malaysia 16150 Kubang Kerian, Kelantan, Malaysia.

Keywords:

cervical intracavitary brachytherapy, organs at risk, PLATO, Oncentra, treatment planning system

Abstract

This is a retrospective study, the organ doses to the bladder and rectum were compared between Nucletron PLATO V14.2.3 (BV) and newer version software Oncentra MasterPlan V4.3 (OMP) treatment planning systems (TPS). The treatment data of 32 intracavitary brachytherapy patients at Hospital Universiti Sains Malaysia from January 2010 to June 2015 were used. These data sets were used for catheter reconstruction for both PLATO and OMP TPS followed by independent verification using Excel. There is no significant difference in mean doses to organs at risk (OARs) that calculated by both TPS (p>0.05). The mean percentage of doses calculated by PLATO TPS for bladder and rectum were 66.58 ± 27.42 %  and 46.27 ± 14.47 % respectively. While the mean percentage of doses for bladder and rectum calculated by OMP TPS were 65.68 ± 24.24 % and 46.46 ± 16.66 respectively. The mean percentage difference in doses comparison between independent verification calculation and PLATO TPS was 1.96 ± 6.00% and then became 6.37 ± 5.17% when it was compared with OMP TPS. Overall, the dose calculation differences for both versions of TPS were within the range recommended by Nuclear Regulatory Commission (NRC). The dose calculations of the two treatment planning systems showed good agreement and both could be used in planning intracavitary brachytherapy for cervical cancer. Whereas Excel based independent verification suitable to be implemented as routine dose verification programme prior to treatment delivery. DOI : http://dx.doi.org/10.17576/JSKM-2021-1901-13

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Published

2021-01-26

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Section

Medical Imaging and Radiation Therapy