Gut Microbiome and Allergic Rhinitis: A New Paradigm in Understanding and Treatment

Abstract

This paper explores the correlation between allergic rhinitis (AR) and gut microbiome, emphasizing the role of intestinal microflora in disease progression. The epidemiological characteristics and pathophysiological basis of AR are initially discussed, highlighting its association with the inflammatory response mediated by immunoglobulin E (IgE). In addition, the classification, diagnosis, and standard treatment options for AR are reviewed, including skin prick testing, serum-specific IgE detection, and allergen-specific immunotherapy. The ensuing sections of the paper explore the mechanism and clinical use of probiotics for modulating the intestinal microbiota, bolstering immune function, and alleviating symptoms of allergic rhinitis, as well as providing an overview of relevant clinical research advancements. The discussion explores the interchange between gut flora and the respiratory system, highlighting the attributes and potential therapeutic applications of probiotics in reducing the risk of allergic rhinitis.